DEA Schedule 2 · South Carolina

Schedule 2 Controlled Substances in South Carolina

High potential for abuse. Accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. No refills permitted.

Common examples: oxycodone, fentanyl, Adderall, Ritalin, morphine

133 Schedule 2 Drugs

Effective in South Carolina (SC)
Generic NameBrand NameDEA Schedule
(S)-Alpha-Methylphenethylamine SulphateSchedule II
acetaminophen and codeine phosphateACETAMINOPHEN AND CODEINE PHOSPHATESchedule II
Alfentanil HClSchedule II
Amaranth, Bamboo, Barley, Buckwheat, Corn, Flax Seed, Lentils, Millet, Milo, Oat, Poppy Seed, Rice, Rye, Sesame, Soybean, Sugarcane, Sunflower Seed, Wheat, Arsenicum Album, Lycopodium Clavatum, Natrum Muriaticum, SulphurGrain and Seed AntigensSchedule II
Amobarbital SodiumSchedule II
amphetamineDYANAVEL XRSchedule II
Amphetamine AspartateSchedule II
Amphetamine Aspratate MonohydrateSchedule II
Amphetamine Extended-ReleaseAmphetamine Extended-ReleaseSchedule II
amphetamine sulfateAMPHETAMINE SULFATESchedule II
Amphetamine Sulfate TabletsAmphetamine sulfateSchedule II
ATROPA BELLADONNA and OPIUMBelladonna and OpiumSchedule II
Bamboo, Barley, Poppy Seed, Corn, Flax Seed, Buckwheat, Millet, Milo, Oat, Rice, Rye, Lentils, Sesame, Amaranth, Soy Bean, Sugarcane, Sunflower Seed, Wheat, Arsenicum Album, Lycopodium Clavatum, Natrum Muriaticum, SulphurGrain and Seed AntigensSchedule II
Benzhydrocodone and AcetaminophenAPADAZSchedule II
Camouflage HydrocodoneSchedule II
cocaine hydrochloridecocaine hydrochlorideSchedule II
cocaine hydrochloride nasalNUMBRINOSchedule II
Codeine PhosphateSchedule II
Codeine Phosphate HemihydrateSchedule II
codeine sulfateCodeine sulfateSchedule II
Coumarinum, Quercetin, Rutin, Bamboo, Barley, Poppy Seed, Corn (Zea Mays), Flax Seed (Linum Usitatissimum), Buckwheat (Fagopyrum Esulentum), Millet, Milo, Oat, Rice, Rye, Lentils, Sesame, Amaranth, Soybean, Sugarcane (Saccharum Officinale), Sunflower Seed, Wheat, Amaranth, Avena Sativa, Natrum Sulphuricum, Sarcolacticum Acidum, Triticum Repens, Adrenocorticotrophin, Sycotic Co BacillusChip CravingsSchedule II
d-Methylphenidate BaseSchedule II
d-Methylphenidate HydrochlorideSchedule II
Dexmethylphenidate HClSchedule II
dexmethylphenidate hydrochlorideFocalin XRSchedule II
DextroamphetamineDextroamphetamineSchedule II
Dextroamphetamine BaseSchedule II
Dextroamphetamine SaccharateSchedule II
dextroamphetamine saccharate and amphetamine aspartate and dextroamphetamine sulfate and amphetamine sulfateDextroamphetamine Saccharate and Amphetamine Aspartate and Dextroamphetamine Sulfate and Amphetamine SulfateSchedule II
Dextroamphetamine Saccharate Fine NPSchedule II
Dextroamphetamine Saccharate NPSchedule II
dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate and amphetamine sulfatedextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate and amphetamine sulfateSchedule II
Dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, amphetamine sulfateDextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, amphetamine sulfateSchedule II
dextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, and amphetamine sulfatedextroamphetamine saccharate, amphetamine aspartate monohydrate, dextroamphetamine sulfate, and amphetamine sulfateSchedule II
dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate and amphetamine sulfateDEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE ASPARTATE, DEXTROAMPHETAMINE SULFATE AND AMPHETAMINE SULFATESchedule II
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine SulfateDextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine SulfateSchedule II
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets, 10 mg,CllDextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets,CIISchedule II
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets, 15 mg,CllDextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets,CIISchedule II
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets, 20 mg,CllDextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets,CIISchedule II
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets, 30 mg,CllDextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets,CIISchedule II
Dextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets, 5 mg,CllDextroamphetamine Saccharate, Amphetamine Aspartate, Dextroamphetamine Sulfate, Amphetamine Sulfate Tablets,CIISchedule II
dextroamphetamine saccharate, amphetamine aspartate, dextroamphetamine sulfate, and amphetamine sulfateDEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE ASPARTATE, DEXTROAMPHETAMINE SULFATE, AND AMPHETAMINE SULFATESchedule II
dextroamphetamine sulfateDEXEDRINE SPANSULESchedule II
Dextroamphetamine Sulfate Fine NPSchedule II
Dextroamphetamine Sulfate NPSchedule II
DEXTROAMPHETAMINE SULFATE, DEXTROAMPHETAMINE SACCHARATE, AMPHETAMINE ASPARTATE MONOHYDRATE, and AMPHETAMINE SULFATESchedule II
Dextroamphetamine Sulfate, Dextroamphetamine Saccharate, Amphetamine Sulfate and Amphetamine AspartateAdderall XRSchedule II
Dextromethadone HydrochlorideSchedule II
Di-tert-butyl ((S)-6-oxo-6-(((S)-1-phenylpropan-2-yl) amino) hexane-1,5-diyl) dicarbamateSchedule II
Dihydrocodeine BitartrateSchedule II
Diphenoxylate HClSchedule II
Diphenoxylate HydrochlorideSchedule II
DIPHENOXYLATE HYDROCHLORIDE and ATROPINE SULFATESchedule II
DIPHENOXYLATE HYDROCHLORIDE WITH ATROPINE SULFATESchedule II
FentanylSchedule II
Fentanyl AlkaloidSchedule II
Fentanyl BaseSchedule II
fentanyl citrateSchedule II
Fentanyl HClSchedule II
fentanyl transdermalFENTANYL TRANSDERMALSchedule II
Hydrocodone APAPHydrocodone APAPSchedule II
hydrocodone bitartrateHysingla ERSchedule II
hydrocodone bitartrate and acetaminophenHydrocodone Bitartrate and AcetaminophenSchedule II
Hydrocodone Bitartrate and AspirinHydrocodone Bitartrate and AspirinSchedule II
Hydrocodone Bitartrate and GuaifenesinOBREDONSchedule II
hydrocodone bitartrate and homatropine methylbromideHydrometSchedule II
hydrocodone bitartrate and homatropine methylbromide oral solutionHydrocodone Bitartrate and Homatropine MethylbromideSchedule II
Hydrocodone Bitartrate and IbuprofenHydrocodone Bitartrate and IbuprofenSchedule II
Hydrocodone Bitartrate Enol Benzoate HClSchedule II
HYDROCODONE BITARTRATE HYDRATESchedule II
Hydrocodone Polistirex and Chlorpheniramine PolistirexHydrocodone Polistirex and Chlorpheniramine Polistirex extended-releaseSchedule II
Hydrocodone/APAPNorcoSchedule II
Hydromorphone HClSchedule II
hydromorphone hydrochlorideDilaudidSchedule II
LDF 3ASchedule II
Levorphanol TartrateLevorphanol TartrateSchedule II
lisdexamfetamineLisdexamfetamine DimesylateSchedule II
lisdexamfetamine dimesylateLISDEXAMFETAMINE DIMESYLATESchedule II
Lisdexamfetamine dimesylate capsulesLisdexamfetamine dimesylateSchedule II
Lisdexfetamine DimesylateSchedule II
Meperidine HClSchedule II
meperidine hydrochlorideSchedule II
MethadoneMethadone HydrochlorideSchedule II
Methadone HclSchedule II
methadone hydrochlorideMETHADOSESchedule II
Methamphetamine HClSchedule II
Methamphetamine HydrochlorideSchedule II
methylphenidateMethylphenidateSchedule II
Methylphenidate BaseSchedule II
Methylphenidate HClMethylphenidate HClSchedule II
methylphenidate hydrochloridemethylphenidate hydrochlorideSchedule II
methylphenidate hydrochloride extended releaseMETHYLPHENIDATE HYDROCHLORIDE EXTENDED RELEASESchedule II
MorphineOpium Tincture DeodorizedSchedule II
morphine sulfateMorphine SulfateSchedule II
morphine tinctureOpium Tincture DeodorizedSchedule II
NabiloneCesametSchedule II
NoroxymorphoneSchedule II
OLICERIDINEOLINVYKSchedule II
Oliceridine FumarateSchedule II
Opium TinctureSchedule II
OripavineSchedule II
OxycodoneOxycodone HydrochlorideSchedule II
oxycodone and acetaminophenOXYCODONE AND ACETAMINOPHENSchedule II
oxycodone and acetaminophen tabletsoxycodone and acetaminophenSchedule II
Oxycodone and AspirinOxycodone and AspirinSchedule II
Oxycodone baseSchedule II
Oxycodone HclSchedule II
OXYCODONE HCL LOW - ALPHA BETA UNSATURATED KETONESchedule II
Oxycodone HydchlorideOxycodone HydchlorideSchedule II
oxycodone hydrochlorideRoxicodoneSchedule II
oxycodone hydrochloride and acetaminophenPERCOCETSchedule II
OXYCODONE HYDROCHLORIDE DSchedule II
Oxycodone Hydrochloride Oral SolutionOxycodone Hydrochloride Oral SolutionSchedule II
Oxycodone/APAPOxycodone/APAPSchedule II
Oxymorphone HClSchedule II
oxymorphone hydrochlorideOxymorphone HydrochlorideSchedule II
pentobarbital sodiumpentobarbital sodiumSchedule II
Phenyl-2-(R,S)-Aminopropane AspartateSchedule II
Phenyl-2-(R,S)-Aminopropane SulfateSchedule II
Phenyl-2-(S)-Aminopropane SaccharateSchedule II
Phenyl-2-(S)-Aminopropane SulfateSchedule II
Powdered OpiumSchedule II
Purified Oxycodone BaseSchedule II
Racemic Amphetamine AspartateSchedule II
Remifentanil HClSchedule II
Remifentanil hydrochlorideRemifentanil hydrochlorideSchedule II
Serdexmethylphenidate and DexmethylphenidateAZSTARYSSchedule II
sufentanilSchedule II
Sufentanil BaseSchedule II
sufentanil citrateSchedule II
tapentadol hydrochlorideNucyntaSchedule II
ThebaineSchedule II
Thebaine CrudeSchedule II

About Schedule 2 Drugs in South Carolina

Schedule 2 controlled substances in South Carolina are regulated under both federal DEA guidelines and South Carolina state pharmacy law. High potential for abuse. Accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence. No refills permitted.

Prescribers and pharmacists in South Carolina must maintain compliance with both federal and state-level scheduling requirements. Some drugs may be classified differently at the state level — always verify the effective schedule for South Carolina before prescribing or dispensing.

For real-time compliance guidance including PDMP requirements, prescribing limits, and transfer rules in South Carolina, use the Controlled Substance Lookup Tool.

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