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25 Schedule 5 Drugs

Effective in South Carolina (SC)

Generic Name	Brand Name	DEA Schedule
Acetaminophen and Codeine Phosphate	Acetaminophen and Codeine Phosphate	Schedule V
brivaracetam	Briviact	Schedule V
Brompheniramine Maleate, Codeine Phosphate, Phenylephrine Hydrochloride	Poly-Tussin AC	Schedule V
Cannabidiol	—	Schedule V
cenobamate	—	Schedule V
Codeine Phosphate and Guaifenesin	Codeine-Guaifenesin	Schedule V
diphenoxylate hydrochloride	—	Schedule V
diphenoxylate hydrochloride and atropine sulfate	Diphenoxylate Hydrochloride and Atropine Sulfate	Schedule V
ganaxolone	ZTALMY	Schedule V
Guaifenesin and Codeine Phosphate	Guaifenesin and Codeine Phosphate	Schedule V
lacosamide	Vimpat	Schedule V
Lacosamide (CIP Process)	—	Schedule V
Lacosamide 100 mg yellow film-coated tablet	—	Schedule V
Lacosamide 150 mg salmon film-coated tablet	—	Schedule V
Lacosamide 200 mg blue film-coated tablet	—	Schedule V
Lacosamide 50 mg pinkish film-coated	—	Schedule V
Lacosamide Oral Solution	Lacosamide Oral Solution	Schedule V
lasmiditan	Reyvow	Schedule V
Lasmiditan hemisuccinate	—	Schedule V
pregabalin	pregabalin	Schedule V
PREGABALIN capsules, CV	PREGABALIN capsules, CV	Schedule V
Pregablin	Pregablin	Schedule V
Promethazine and Phenylephrine Hydrochloride and Codeine Phosphate	Promethazine VC with Codeine Oral Solution	Schedule V
promethazine hydrochloride and codeine phosphate	promethazine hydrochloride and codeine phosphate	Schedule V
Promethazine, Phenylephrine, Codeine	Promethazine HCl, Phenylephrine HCl, Codeine Phosphate	Schedule V

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About Schedule 5 Drugs in South Carolina

Schedule 5 controlled substances in South Carolina are regulated under both federal DEA guidelines and South Carolina state pharmacy law. Lowest potential for abuse. Contains limited quantities of certain narcotics. Some may be available over-the-counter in certain states.

Prescribers and pharmacists in South Carolina must maintain compliance with both federal and state-level scheduling requirements. Some drugs may be classified differently at the state level — always verify the effective schedule for South Carolina before prescribing or dispensing.

For real-time compliance guidance including PDMP requirements, prescribing limits, and transfer rules in South Carolina, use the Controlled Substance Lookup Tool.

Other Schedules in South Carolina

Schedule 2 Schedule 3 Schedule 4

Schedule 5 Drugs in Other States

Missouri North Dakota Wisconsin Georgia District of Columbia Colorado New York New Hampshire

Rx Agent · South Carolina

What are the prescribing rules for Schedule 5 in South Carolina?

✓ PDMP requirements✓ Refill & day supply limits✓ DEA registration rules✓ Cited to statute